Psychedelic Medicine


Psychedelic Medicine


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Mescaline is found in a range of cacti. It is the primary psychoactive alkaloid in these cacti, the most famous of which are San Pedro and Peyote. It can be given as a powder, capsules, or a brew. 

Mescaline has been used for millennia in Native American ceremonies. It is known to make the ordinary seem extraordinary and mystical. It may also lead to distortion of the environment and feelings from euphoria to increased connected thought and empathy.

Legal usage in the US is limited to the form of peyote and is only available to certain Native Americans. 


Systematic review and meta-analysis of randomized controlled trials of ketamine in the treatment of refractory anxiety spectrum disorders

Elizabeth Whittaker, Alisher R. Dadabayev, Sonalee A. Joshi, and Paul Glue
December 2021

Efficacy and safety of esketamine nasal spray by sex in patients with treatment-resistant depression: findings from short-term randomized, controlled trials

Robyn R. Jones, Marlene P. Freeman, Susan G. Kornstein, Kimberly Cooper, Ella J. Daly, Carla M. Canuso & Susan Nicholson
January 2022

The emerging science of microdosing: A systematic review of research on low dose psychedelics (1955 – 2021)

Vince Polito, Paul Liknaitzky
December 2021

Acute Effects of Psilocybin After Escitalopram or Placebo Pretreatment in a Randomized, Double-Blind, Placebo-Controlled, Crossover Study in Healthy Subjects

Anna M. Becker, Friederike Holze, Tanja Grandinetti, Aaron Klaiber, Vanja E. Toedtli, Karolina E. Kolaczynska, Urs Duthaler, Nimmy Varghese, Anne Eckert, Edna Grünblatt, Matthias E. Liechti
November 2021


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