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Mescaline is found in a range of cacti. It is the primary psychoactive alkaloid in these cacti, the most famous of which are San Pedro and Peyote. It can be given as a powder, capsules, or a brew. 

Mescaline has been used for millennia in Native American ceremonies. It is known to make the ordinary seem extraordinary and mystical. It may also lead to distortion of the environment and feelings from euphoria to increased connected thought and empathy.

Legal usage in the US is limited to the form of peyote and is only available to certain Native Americans. 


The Potential Role of Serotonergic Hallucinogens in Depression Treatment

Dominika Psiuk, Emilia Nowak, Krystian Cholewa, Urszula Łopuszańska, and Marzena Samardakiewicz
August 2021

Anti-inflammatory and analgesic actions of bufotenine through inhibiting lipid metabolism pathway

Jiaojiao Wang, Dihui Xu, Lili Shen, Jing Zhou, Xiang Lv, Hongyue Ma, Nianguang Li, Qinan Wu, Jinao Duan
August 2021

Psilocybin as a Novel Pharmacotherapy for Treatment-Refractory Anorexia Nervosa

Sarah-Catherine Rodan, Phillip Aouad, Iain S McGregor, Sarah Maguire
June 2021

Cognitive Behavioral Therapy to Sustain the Antidepressant Effects of Ketamine in Treatment-Resistant Depression: A Randomized Clinical Trial

Samuel T Wilkinson, DaShaun Wright, Madonna K Fasula, Lisa Fenton, Matthew Griepp, Robert B Ostroff, Gerard Sanacora
May 2017


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