5-MeO-DMT Scientific Research with Dr. Joseph Barsuglia
In this episode, Dr. Barsuglia discusses what happens to the body when 5-MEO-DMT is consumed. He also discusses the origins and history of 5-MEO-DMT, as well as some of the scientific research being conducted on the molecule. He also shares some research on how he observed the mystical effects 5-MEO-DMT had on patients and some of the consistent experiences patients described.
The increasing popularity of this psychedelic often brings up a discussion on the environmental impact of harvesting Sonoran Desert toads. Dr. Barsuglia uses this to discuss differences between synthetic vs naturally occurring 5-MEO-DMT, and how synthetic developments can help protect the environment and preserve tribal tradition.
In This Episode
• The sources of 5-MEO-DMT and how it is used
• The historical, cultural, and environmental significance of 5-MEO-DMT
• The effects of 5-MEO-DMT on the body and common experiences from participants
• Current scientific research on this plant medicine
• The differences between natural and synthetic 5-MEO-DMT
“Some kind of basic science studies on cell lines that showed that 5-MEO-DMT does in fact stimulate brain cell growth, antidepressant properties, and might boost the immune system.” [13:24]
“In many psychedelics, you are getting formed visuals, you can kind of interact with what’s happening. This medicine kind of takes you beyond your biography, beyond your memory, beyond form into a very energetic experience.” [16:07]
“80 percent, I think, of people that had this experience said it was profoundly sacred or holy.” [28:48]
“I also think that people don’t need to be demonized that are using this medicine.” [51:31]
- Intensity of Mystical Experiences Occasioned by 5-MeO-DMT and Comparison With a Prior Psilocybin Study
- A case report SPECT study and theoretical rationale for the sequential administration of ibogaine and 5-MeO-DMT in the treatment of alcohol use disorder
- The epidemiology of 5-methoxy-N, N-dimethyltryptamine (5-MeO-DMT) use: Benefits, consequences, patterns of use, subjective effects, and reasons for consumption
- 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) used in a naturalistic group setting is associated with unintended improvements in depression and anxiety
* The Psychedelic Medicine Podcast has allowed the Psychedelic Medicine Association to post episodes as an educational resource, and in return the PMA is hosting the podcast show notes.